Everquest slow focus change

I just started using ISBoxer with EVE and Everquest. I've setup 4 accounts on EVE and it works perfectly, swapping is pretty much instant. On Everquest, I'm running two accounts setup so each one has it's own monitor. The problem I'm having is when I click on the non-current window to make it have focus, everything freezes for a couple minutes. Once it unfreezes, I can swap the second and primary displays with my hotkey and that is pretty much instant. Is it normal for Everquest to hang when you try to change the window you are directly controlling or do I just have it setup incorrectly? I tried changing which cpu core each instance uses but that didn't seem to help. I have an ATI graphics card and it has given me problems with certain games, not sure if that is the culprit.

Here is my ISBoxer setup
http://www.privatepaste.com/c86f62a5ab

And some system specs
Operating System: Windows 7 Home Premium 64-bit (6.1, Build 7600) (7600.win7_gdr.100618-1621)
Language: English (Regional Setting: English)
System Manufacturer: Alienware
System Model: Aurora
BIOS: Default System BIOS
Processor: Intel(R) Core(TM) i7 CPU 920 @ 2.67GHz (8 CPUs), ~2.7GHz
Memory: 6144MB RAM
Available OS Memory: 6134MB RAM
Page File: 3107MB used, 9160MB available
DirectX Version: DirectX 11


Card name: ATI Radeon HD 5800 Series
Manufacturer: ATI Technologies Inc.
Chip type: ATI display adapter (0x6898)
DAC type: Internal DAC(400MHz)
Device Key: Enum\PCI\VEN_1002&DEV_6898&SUBSYS_0B001002&REV_00
Display Memory: 3823 MB
Dedicated Memory: 1012 MB
Shared Memory: 2811 MB