Do I really need all of the data in the MPQ folder?

My MPQ folder basically looks like this

http://i.imgur.com/ZJbzTfS.png

The folder currently contains 67GB of the 78GB in the game folder. This is taking up too much space in my 256GB boot drive. How do I figure out which folders I need for my current quad box configuration so I can delete the others?

Thanks

[lax]

You do have extra Cache folders, unless you have custom Virtual Files specifying that they should be used ...

You should only need:
1. Cache
2. Cache-1
3. Cache-2
4. Cache-3
5. Cache-4

I did have some issues with my configuration a few months back with the new app launcher from bnet and I think I created some new cache folders trying to make a fresh start. I will temporarily delete all the other cache folders and try to launch the clients. Thanks for the fast response.

**edit**

I deleted all the other cache folders and it shrunk my game folder to 36GB. Thank you for your help!