Unable to cast spells in certain area's of the screen

Posted this in the isboxer chatroom, doesn't hurt to ask it here as well. When I'm multiboxing diablo with 4 copies there are certain area's on my screen where I can't seem to rightclick/cast spells. This appositely has something to do with regions, but that's all I know. Does someone recognise this issue and maybe have a fix for this?

*bump*

[lax]

... which areas?

This appositely has something to do with regions

Did you set up Repeater Regions inside the game at some point? Press Ctrl+Shift+Alt+G to bring up editing mode, if red or green boxes suddenly appear in the trouble areas that might give us a hint