New to ISboxer

I play diablo 3 reaper of souls and I am having trouble controlling the mouse. I am using 4 accounts and i tried lowering the settings for my other accounts and kept my original (the one i use) as high settings. Now the mouse is way off point and i cant seem to go back to the original settings. somebody please help me

[MiRai]

It pretty much comes down to resolution, display mode, aspect ratio, and instant swapping being enabled.

https://www.youtube.com/watch?v=ftvE_gBtMJU

Also, this: viewtopic.php?f=40&t=3206