Odd behavior since Win 10 upgrade

I'm noticing that since upgrading to windows 10 that when I start my clients and the dxnothing window, they no longer appear central on the chosen monitor. They now start misaligned and go off the side of the screen. I've checked the settings and everything seems ok as per before the upgrade. Anyone else had this issue?

This can be disregarded now as I found the issue. Incase anyone else has the same problem, it seems that after an upgrade the Win10 UI scaling isn't always set to 100% but some odd custom value.

Just go to display settings and move the "Size of text, apps and other items" slider up and back down to 100%, then log off and the issue is fixed.