Mon Sep 10, 2012 8:36 am by lax
Go to the File menu, select Clear, and run the Quick Set up Wizard again.

You can, of course, save your current configuration as a backup filename first. You can also open up a second instance of ISBoxer in order to look at two profiles at once (e.g. your current one and a clean one), and you can use the Copy/Paste functionality (right click and select Copy to Clipboard or Paste from Clipboard) to copy things between them as well.
Note that if you're copying things between them manually you may need to know some more things that you don't need to know if you're using the wizard, for example that your Key Maps might need to be assigned to your Character Set.